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Bcl-2 antibody (pSer70)

BCL2 Reactivity: Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

Catalog No. ABIN1450521

Datasheet as PDF

Target See all Bcl-2 (BCL2) Antibodies

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
Binding Specificity
48

35

27

23

22

21

16

16

16

11

10

8

8

7

7

7

6

6

5

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 36-85, pSer70
Reactivity
402

159

159

34

23

22

15

9

6

5

5

1

1

1

1

1
Mouse, Rat
Host
322

107

5

2

1
Rabbit
Compatible Secondaries
Clonality
318

118
Polyclonal
Conjugate
193

28

27

20

20

11

8

8

8

8

8

8

8

8

8

8

8

5

5

5

5

5

5

2

2

2

2

2

2

2

2

1

1

1

1
This Bcl-2 antibody is un-conjugated
Application
332

175

139

106

95

90

80

60

55

30

23

22

18

8

8

7

5

4

2

2

1

1

1

1

1

1
Western Blotting (WB), ELISA

Specificity

BCL2 (Phospho-Ser70) Antibody detects endogenous levels of BCL2 only when phosphorylated at Ser70.
PhosphorylationM:S70, R:S70

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Immunogen

The antiserum was produced against synthesized peptide derived from human BCL2 around the phosphorylation site of Ser70.

Isotype

IgG

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BCL2 Reactivity: Human FACS Host: Mouse Monoclonal Bcl-2-100 PE

Application Notes

WB: 1:500~1:1000 ELISA: 1:10000

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Stable at -20°C for at least 1 year.
Target

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name

BCL2 (BCL2 Products)

Background

Synonyms: Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, BCL2
NCBI Gene Symbol: BCL2

Molecular Weight

26 kDa

Gene ID

596

OMIM

151430

UniProt

P10415

Pathways

MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling