Huntingtin antibody (pSer421)
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- Target See all Huntingtin (HTT) Antibodies
- Huntingtin (HTT)
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Binding Specificity
- AA 387-436, pSer421
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Huntingtin antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Specificity
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Huntingtin (Phospho-Ser421) Antibody detects endogenous levels of Huntingtin only when phosphorylated at Ser421.
PhosphorylationH:S421, M:S398, R:S389
- Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Immunogen
- The antiserum was produced against synthesized peptide derived from human Huntingtin around the phosphorylation site of Ser421.
- Isotype
- IgG
- Top Product
- Discover our top product HTT Primary Antibody
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- Application Notes
- IHC: 1:50~1:100 ELISA: 1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable at -20°C for at least 1 year.
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- Target
- Huntingtin (HTT)
- Alternative Name
- Huntingtin (HTT Products)
- Synonyms
- HTT antibody, hd antibody, ZHD antibody, CG9995 antibody, Dmel\\CG9995 antibody, HD antibody, Hsap\\HD antibody, Htt antibody, dHtt antibody, dhtt antibody, SLC6A4 antibody, huntington antibody, it15 antibody, htt antibody, IT15 antibody, AI256365 antibody, C430023I11Rik antibody, Hd antibody, Hdh antibody, huntingtin antibody, HTT antibody, htt antibody, LOC373520 antibody, Htt antibody
- Background
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Synonyms: HD, HD protein, HDH, Huntington's disease protein, Huntington's disease protein homolog, IT15
NCBI Gene Symbol: HTT
- Molecular Weight
- 347 kDa
- Gene ID
- 3064
- OMIM
- 143100
- UniProt
- P42858
- Pathways
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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