GFRA4 antibody

Catalog No. ABIN1450233

Product Details anti-GFRA4 Antibody

Target: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This GFRA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: GFRα-4 belongs to the GDNF receptor family. It is aglycosyl-phosphatidylinositol (GPI)-linked cell surface receptor for persephin,and mediates activation of the RET tyrosine kinase receptor

Characteristics: Mono- and polyclonal antibodies to human neural growth factors and neural growth factor receptors.

Purification: GFRa-4 affinity purified

Isotype: IgY

Application Details

Application Notes: Westernimmunoblotting, recommended dilution  1:5000 to 1:10 000, ELISA: 1:160 000 to 1:320 000, IF 1:1000 to1:3000. Polyclonal antibody working titer has to be established practically for each particularantigen and assay format

Comment:

Synonym: GDNF receptor alpha-4, Persephin receptor

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml

Buffer: PBS pH 7.4

Handling Advice: Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles as productdegradation may result

Storage: -20 °C/-80 °C

Storage Comment: This product is shipped in non-frozen liquid form in ambient conditions

Target Details for GFRA4

Target: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Alternative Name: GFRa-4 (GFRA4 Products)

Synonyms: zgc:171814 antibody, AW060733 antibody, G630015H18Rik antibody, GDNF family receptor alpha 4 antibody, GDNF family receptor alpha 4a antibody, glial cell line derived neurotrophic factor family receptor alpha 4 antibody, GFRA4 antibody, gfra4a antibody, Gfra4 antibody

Background: Recombinant His-tagged human GFRa-4 protein produced using CHO-based cell line.For production of hGFRa-4, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purifiedby Ni-affinity chromatography following gel-filtration from cell culturesupernatant

UniProt: Q9GZZ7