GBP6 antibody (C-Term)

Catalog No. ABIN1450119

Product Details anti-GBP6 Antibody

Target: GBP6 (Guanylate Binding Protein 6 (GBP6))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid synthetic peptide near the carboxy terminus of Human GBP6

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GBP6

Target: GBP6 (Guanylate Binding Protein 6 (GBP6))

Alternative Name: GTP-Binding Protein 6 / GBP6 (GBP6 Products)

Synonyms: AI595338 antibody, Mpa2l antibody, guanylate binding protein 6 antibody, guanylate binding protein family member 6 antibody, Gbp6 antibody, GBP6 antibody

Background: The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3). GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP. The precise function of GBP6 is still under investigation .Synonyms: Guanine nucleotide-binding protein 6, Guanylate-binding protein 6

Gene ID: 163351

NCBI Accession: NP_940862

Pathways: Cellular Response to Molecule of Bacterial Origin