PPHLN1 antibody (Middle Region)

Catalog No. ABIN1450117

Product Details anti-PPHLN1 Antibody

Target: PPHLN1 (Periphilin 1 (PPHLN1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPHLN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the center of Human Periphilin

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PPHLN1

Target: PPHLN1 (Periphilin 1 (PPHLN1))

Alternative Name: Periphilin 1 (PPHLN1 Products)

Background: Periphilin, known as PPHLN1 or gastric cancer antigen Ga50, plays a role in epithelial differentiation and contributes to epidermal integrity and barrier formation. It interacts with periplakin, a known precursor of the cornified cell envelope. Periphilin 1 is ubiquitously expressed and localizes to nucleus and cytoplasm. Existing as eight alternatively spliced isoforms, Periphilin is highly insoluble and contains a putative nuclear localization signal (NLS) within its N-terminal half, a prerequisite for the formation of insoluble complexes and a possible caspase recognition sequence and a potential nuclear export signal. Periphilin may play an important role in the nervous system.Synonyms: Ga50, Gastric cancer antigen Ga50, HSPC206, HSPC232, PPHLN1, Periphilin-1

Gene ID: 51535

NCBI Accession: NP_958848