TMPRSS11A antibody (C-Term)

Catalog No. ABIN1450094

Product Details anti-TMPRSS11A Antibody

Target: TMPRSS11A (Transmembrane Protease, Serine 11A (TMPRSS11A))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Chicken

Clonality: Polyclonal

Conjugate: This TMPRSS11A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: ECRG1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ECRG1.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for TMPRSS11A

Target: TMPRSS11A (Transmembrane Protease, Serine 11A (TMPRSS11A))

Alternative Name: ECRG1 (TMPRSS11A Products)

Synonyms: ECRG1 antibody, Gm7 antibody, transmembrane protease, serine 11A antibody, transmembrane protease serine 11A antibody, transmembrane protease, serine 11a antibody, TMPRSS11A antibody, LOC517049 antibody, LOC100482139 antibody, LOC100525933 antibody, Tmprss11a antibody

Background: Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.Synonyms: Airway trypsin-like protease 1, Esophageal cancer-susceptibility gene 1 protein, HATL1, HESP, TMPRSS11A

Gene ID: 339967

UniProt: Q6ZMR5