Ly6k antibody (N-Term)

Catalog No. ABIN1450086

Product Details anti-Ly6k Antibody

Target: Ly6k (Lymphocyte Antigen 6 Complex, Locus K (Ly6k))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ly6k antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal LY6K antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of Human LY6K

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Ly6k

Target: Ly6k (Lymphocyte Antigen 6 Complex, Locus K (Ly6k))

Alternative Name: LY6K (Ly6k Products)

Synonyms: LY6K antibody, CT97 antibody, HSJ001348 antibody, ly-6K antibody, 2410015A16Rik antibody, 3110035B01Rik antibody, mLy-6K antibody, lymphocyte antigen 6 family member K antibody, lymphocyte antigen 6 complex, locus K antibody, LY6K antibody, Ly6k antibody

Background: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.Synonyms: CO16, Ly-6K, Lymphocyte antigen 6K

Gene ID: 54742