NSRP1 antibody (C-Term)

Catalog No. ABIN1450062

Product Details anti-NSRP1 Antibody

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This NSRP1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the carboxy terminus of Human CCDC55

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NSRP1

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Alternative Name: CCDC55 (NSRP1 Products)

Synonyms: 8030451K07 antibody, AI851076 antibody, AL022898 antibody, NSpr70 antibody, NSrp70 antibody, Nsrp1 antibody, CCDC55 antibody, HSPC095 antibody, Ccdc55 antibody, RGD1309863 antibody, fc14d05 antibody, wu:fc14d05 antibody, zgc:152777 antibody, nuclear speckle regulatory protein 1 antibody, nuclear speckle splicing regulatory protein 1 antibody, Nsrp1 antibody, NSRP1 antibody, nsrp1 antibody

Background: CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection. Nuclear speckles are known to be the storage sites of mRNA splicing regulators. CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo. It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing. Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.Synonyms: Coiled-coil domain-containing protein 55, HSPC095, NSrp70

Gene ID: 84081

NCBI Accession: NP_115517