UHRF1BP1L antibody (Middle Region)
UHRF1BP1L
Reactivity: Human, Mouse
WB, IF, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
(1 reference)-
- Target See all UHRF1BP1L Antibodies
- UHRF1BP1L (UHRF1 (ICBP90) Binding Protein 1-Like (UHRF1BP1L))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UHRF1BP1L antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 17 amino acid synthetic peptide near the center of Human UHRF1BP1L
- Isotype
- IgG
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anti-UHRF1 (ICBP90) Binding Protein 1-Like (UHRF1BP1L) (AA 1-522) antibody
UHRF1BP1L Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 705-17, (2008) (PubMed).
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: "ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 705-17, (2008) (PubMed).
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- Target
- UHRF1BP1L (UHRF1 (ICBP90) Binding Protein 1-Like (UHRF1BP1L))
- Alternative Name
- UHRF1BP1L (UHRF1BP1L Products)
- Background
- The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1-like (UHRF1BP1L) is closely related to UHRF1BP1, also known as ICBP90, a transcription and cell cycle regulator that specifically binds to the histone H3 N-terminal tail. While little is known of UHRF1BP1L, UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells, suggesting that UHRF1BP1L may also be involved in chromatin regulation and cell proliferation.Synonyms: KIAA0701, UHRF1-binding protein 1-like
- Gene ID
- 23074
- NCBI Accession
- NP_055869
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