SHIP164 antibody, 2010319N22Rik antibody, 4930506D01Rik antibody, AA589495 antibody, C80672 antibody, E030041M21Rik antibody, mKIAA0701 antibody, MGC80013 antibody, UHRF1BP1L antibody, si:dkeyp-90a8.1 antibody, UHRF1 binding protein 1 like antibody, UHRF1 (ICBP90) binding protein 1-like antibody, UHRF1 binding protein 1-like antibody, UHRF1 binding protein 1-like L homeolog antibody, UHRF1BP1L antibody, Uhrf1bp1l antibody, uhrf1bp1l.L antibody, uhrf1bp1l antibody
Background
The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1-like (UHRF1BP1L) is closely related to UHRF1BP1, also known as ICBP90, a transcription and cell cycle regulator that specifically binds to the histone H3 N-terminal tail. While little is known of UHRF1BP1L, UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells, suggesting that UHRF1BP1L may also be involved in chromatin regulation and cell proliferation.Synonyms: KIAA0701, UHRF1-binding protein 1-like