SHROOM3 antibody (Middle Region)

Catalog No. ABIN1450022

Product Details anti-SHROOM3 Antibody

Target: SHROOM3 (Shroom Family Member 3 (SHROOM3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHROOM3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal SHROOM3 antibody was raised against an 18 amino acid peptide near the center of Human SHROOM3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SHROOM3

Target: SHROOM3 (Shroom Family Member 3 (SHROOM3))

Alternative Name: SHROOM3 (SHROOM3 Products)

Synonyms: APXL3 antibody, SHRM antibody, ShrmL antibody, AL022960 antibody, D5Ertd287e antibody, Shrm antibody, Shrm3 antibody, RGD1310470 antibody, apxl3 antibody, shrm antibody, shroom family member 3 antibody, shroom family member 3 L homeolog antibody, SHROOM3 antibody, shroom3 antibody, Shroom3 antibody, shroom3.L antibody

Background: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM3 is an actin-binding protein is a regulator of the microtubule cytoskeleton during epithelial morphogenesis and is sufficient and necessary to induce a redistribution of the microtubule regulator gamma-tubulin. It is necessary for both apiscobasal cell elongation and apical constriction in the neural epithelium (2,3) SHROOM3 has also been shown to be essential for cell shape changes and morphogenesis in the developing vertebrate gut, with its transcription relying on the Pitx1 transcription factor.Synonyms: APXL3, F-actin-binding, SHRM, SHROOM family member 3, ShrmL

Molecular Weight: 220 kDa

Gene ID: 57619

NCBI Accession: NP_065910

Pathways: Tube Formation, Asymmetric Protein Localization