SGSM1 antibody (Middle Region)

Catalog No. ABIN1449980

Product Details anti-SGSM1 Antibody

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGSM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for SGSM1

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Alternative Name: SGSM1 (SGSM1 Products)

Synonyms: RUTBC2 antibody, 2410098H20Rik antibody, AA408781 antibody, D5Bwg1524e antibody, E130107M15 antibody, NuIP antibody, Rutbc2 antibody, small G protein signaling modulator 1 antibody, SGSM1 antibody, Sgsm1 antibody

Background: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.Synonyms: RUTBC2, Small G protein signaling modulator 1

Molecular Weight: 126 kDa

Gene ID: 129049

NCBI Accession: NP_001035037