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KCP antibody (C-Term)

KCP Reactivity: Human, Rat, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1449940
  • Target See all KCP Antibodies
    KCP (Kielin/Chordin-Like Protein (KCP))
    Binding Specificity
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 2
    Rabbit
    Clonality
    • 2
    Polyclonal
    Conjugate
    • 2
    This KCP antibody is un-conjugated
    Application
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    15 amino acid synthetic peptide near the carboxy terminus of Human CRIM2
    Isotype
    IgG
    Top Product
    Discover our top product KCP Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    KCP (Kielin/Chordin-Like Protein (KCP))
    Alternative Name
    CRIM2 (KCP Products)
    Synonyms
    CRIM2 antibody, KCP1 antibody, NET67 antibody, AW060220 antibody, CRIM-2 antibody, Crim2 antibody, Gm793 antibody, KCP-1 antibody, RGD1561119 antibody, crim2 antibody, kielin/chordin-like protein antibody, kielin/chordin-like protein L homeolog antibody, KCP antibody, LOC515624 antibody, Kcp antibody, kcp.L antibody
    Background
    CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-beta1, suppressing activin- and TGF-beta1-dependent transcription.Synonyms: CRIM-2, Cysteine-rich motor neuron 2 protein, KCP1, NET67, kielin/chordin-like protein
    Gene ID
    375616
    NCBI Accession
    NP_001129386
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