×
For best experience we recommend to activate Javascript in your browser.
KCP antibody (C-Term)
KCP
Reactivity: Human, Rat, Mouse
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KCP Antibody
(hide)
Target
See all KCP Antibodies
KCP
(Kielin/Chordin-Like Protein (KCP))
Binding Specificity
All epitopes for KCP antibodies
C-Term
Reactivity
All reactivities for KCP antibodies
Human, Rat, Mouse
Host
All hosts for KCP antibodies
Rabbit
Clonality
All clonalities for KCP antibodies
Polyclonal
Conjugate
All conjugates for KCP antibodies
This KCP antibody is un-conjugated
Application
Western Blotting (WB), Enzyme Immunoassay (EIA)
Purification
Affinity chromatography purified via peptide column
Immunogen
15 amino acid synthetic peptide near the carboxy terminus of Human CRIM2
Isotype
IgG
Top Product
Discover our top product KCP Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for KCP
(hide)
Target
KCP
(Kielin/Chordin-Like Protein (KCP))
Alternative Name
CRIM2 (KCP Products )
Synonyms
CRIM2 antibody, KCP1 antibody, NET67 antibody, AW060220 antibody, CRIM-2 antibody, Crim2 antibody, Gm793 antibody, KCP-1 antibody, RGD1561119 antibody, crim2 antibody, kielin/chordin-like protein antibody, kielin/chordin-like protein L homeolog antibody, KCP antibody, LOC515624 antibody, Kcp antibody, kcp.L antibody
Background
CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-beta1, suppressing activin- and TGF-beta1-dependent transcription.Synonyms: CRIM-2, Cysteine-rich motor neuron 2 protein, KCP1, NET67, kielin/chordin-like protein
Gene ID
375616
NCBI Accession
NP_001129386
Recently viewed
(hide)