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Centriolin antibody (C-Term)

CNTRL Reactivity: Human, Mouse, Rat WB, EIA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1449934
  • Target See all Centriolin (CNTRL) Antibodies
    Centriolin (CNTRL)
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 14
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 14
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Centriolin antibody is un-conjugated
    Application
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse, Rat.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid synthetic peptide near the carboxy terminus of Human CCP110
    Isotype
    IgG
    Top Product
    Discover our top product CNTRL Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Centriolin (CNTRL)
    Alternative Name
    CEP110 (CNTRL Products)
    Synonyms
    CEP1 antibody, CEP110 antibody, FAN antibody, bA165P4.1 antibody, Cep1 antibody, Cep110 antibody, 6720467O09Rik antibody, AA968343 antibody, Cntrl antibody, IB3/5 antibody, Ma2a8 antibody, b2b1468Clo antibody, centriolin antibody, CNTRL antibody, Cntrl antibody
    Background
    CCP110 is a centrosomal protein required for the centrosome to function as a microtubule organizing center and plays an essential role in centrosome duplication. It is a target of cyclin-dependent kinases (CDKs), disruption of CCP110 phosphorylation leads to unscheduled centrosome separation and polyploidy. CCP110 is also a target of SCF (Cyclin F) ubiquitin ligase complex, leading to its degradation, suggesting that this complex controls centrosome homeostasis and mitotic fidelity through CCP110 degradation. The centriolar kinesin Kif24 also interacts with CP110 and remodel microtubules and regulate ciliogenesis.Synonyms: CP110, Centrosomal protein of 110 kDa, KIAA0419
    Gene ID
    9738
    NCBI Accession
    NP_001185951
    Pathways
    M Phase, SARS-CoV-2 Protein Interactome
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