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ZNF521 antibody (N-Term)

ZNF521 Reactivity: Human WB, EIA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1449926
  • Target See all ZNF521 Antibodies
    ZNF521 (Zinc Finger Protein 521 (ZNF521))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 7
    • 2
    • 1
    Human
    Host
    • 9
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 9
    This ZNF521 antibody is un-conjugated
    Application
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid synthetic peptide near the amino terminus of Human ZNF521
    Isotype
    IgG
    Top Product
    Discover our top product ZNF521 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ZNF521 (Zinc Finger Protein 521 (ZNF521))
    Alternative Name
    ZNF521 (ZNF521 Products)
    Synonyms
    Znf521 antibody, EHZF antibody, Evi3 antibody, B930086A16Rik antibody, zinc finger protein 521 antibody, zinc finger protein 521 S homeolog antibody, Zfp521 antibody, ZNF521 antibody, znf521.S antibody
    Background
    The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors . ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis .Synonyms: EHZF, Early hematopoietic zinc finger protein, LIP3, LYST-interacting protein 3, Zinc finger protein 521
    Gene ID
    25925
    NCBI Accession
    NP_056276
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