AFF2 antibody (N-Term)
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- Target See all AFF2 Antibodies
- AFF2 (AF4/FMR2 Family, Member 2 (AFF2))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AFF2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MDLFDFFRDW DLEQQCHYEQ DRSALKKREW ERRNQEVQQE DDLFSSGFDL
- Cross-Reactivity (Details)
- Species reactivity (expected):Mouse, Rat, Horse, Rabbit, Guinea PigSpecies reactivity (tested):Human
- Purification
- Purified using peptide immunoaffinity column
- Immunogen
- Synthetic peptide directed towards the N terminal of human AFF2
- Top Product
- Discover our top product AFF2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- Target
- AFF2 (AF4/FMR2 Family, Member 2 (AFF2))
- Alternative Name
- AFF2 / FMR2 (AFF2 Products)
- Synonyms
- FMR2 antibody, FMR2P antibody, FRAXE antibody, MRX2 antibody, OX19 antibody, Fmr2 antibody, Ox19 antibody, Oxh antibody, AF4/FMR2 family member 2 antibody, AF4/FMR2 family, member 2 antibody, AFF2 antibody, Aff2 antibody
- Background
- AFF2 is a RNA-binding protein and might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. Defects in AFF2 are the cause of mental retardation X-linked associated with fragile site FRAXE (MRFRAXE). A form of mild to moderate mental retardation associated with learning difficulties, communication deficits, attention problems, hyperactivity, and autistic behavior. It is associated with a fragile site on chromosome Xq28.Synonyms: AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, Protein Ox19
- Gene ID
- 2334
- NCBI Accession
- NP_002016
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