SBDS antibody (N-Term)
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- Target See all SBDS Antibodies
- SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))
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Binding Specificity
- AA 1-250, N-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SBDS antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Protein-G affinity chromatography
- Immunogen
- Recombinant human SBDS (1-250aa) purified from E. coli
- Clone
- AT1E8
- Isotype
- IgG2b
- Top Product
- Discover our top product SBDS Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))
- Alternative Name
- SBDS (SBDS Products)
- Synonyms
- cgi-97 antibody, sds antibody, swds antibody, zgc:56700 antibody, SDS antibody, SWDS antibody, 4733401P19Rik antibody, AI836084 antibody, CGI-97 antibody, SBDS ribosome assembly guanine nucleotide exchange factor antibody, hypothetical protein antibody, SBDS, ribosome maturation factor antibody, SBDS ribosome assembly guanine nucleotide exchange factor S homeolog antibody, SBDS ribosome maturation factor antibody, sbds antibody, LOAG_04440 antibody, sbds.S antibody, SBDS antibody, Sbds antibody
- Background
- The Shwachman-Bodian-Diamond syndrome (SBDS) is 249 amino acid ribosome maturation protein. The precise function of the SBDS protein is not known but it appears to play an important role in actin cytoskeletal function and mitotic spindle stabilization. Also, SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Mutations in the SBDS gene cause Shwachman-Diamond syndrome (SDS). SDS is an autosomal recessive disorder with clinical features that include pancreatic exocrine insufficiency, haematological dysfunction and skeletal abnormalities.Synonyms: Ribosome maturation protein SBDS, Shwachman-Bodian-Diamond syndrome protein
- Gene ID
- 51119
- NCBI Accession
- NP_057122
- UniProt
- Q9Y3A5
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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