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NUMA1 antibody

NUMA1 Reactivity: Human WB, IF, IP Host: Mouse Monoclonal C02142 unconjugated
Catalog No. ABIN1449239
  • Target See all NUMA1 Antibodies
    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
    Reactivity
    • 81
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 69
    • 12
    Mouse
    Clonality
    • 69
    • 12
    Monoclonal
    Conjugate
    • 35
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NUMA1 antibody is un-conjugated
    Application
    • 28
    • 28
    • 26
    • 18
    • 16
    • 15
    • 14
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Specificity
    This antibody reacts with human NuMA.
    Purification
    Protein A agarose
    Immunogen
    Protein fraction extracted from the mitotic chromosome
    Clone
    C02142
    Isotype
    IgG1
    Top Product
    Discover our top product NUMA1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Upon receipt, store (in aliqouts) at -20 °C.
  • Target
    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
    Alternative Name
    NuMA (NUMA1 Products)
    Synonyms
    NUMA antibody, 6720401E04Rik antibody, AA764025 antibody, AL022610 antibody, AU014979 antibody, NUMA1 antibody, NuMA antibody, SP-H antibody, numa antibody, numa1 antibody, nuclear mitotic apparatus protein 1 antibody, nuclear mitotic apparatus protein 1 S homeolog antibody, NUMA1 antibody, Numa1 antibody, numa1 antibody, numa1.S antibody
    Background
    NuMA (Nuclear Mitotic Apparatus Protein) is involved in maintenance of nuclear structure and in the assembly of the mitotic spindle. During interphase, NuMA is present throughout the nucleus, and during mitosis, it localizes to the spindle. It associates with microtubule motors during mitosis, and plays an essential role in anchoring microtubule ends to the spindle poles. NuMA is an autoantigen, and some individuals with connective tissue disease or other autoimmune disorders have antibodies directed against the NuMA protein. Recent data suggests NuMA (240 kDa) is cleaved to a 180-200 kDa form during apoptosis.Synonyms: NUMA1, Nuclear mitotic apparatus protein 1, SP-H antigen
    Molecular Weight
    240 kDa
    Gene ID
    4926
    NCBI Accession
    NP_006176
    UniProt
    Q14980
    Pathways
    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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