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BAFF antibody

TNFSF13B Reactivity: Human WB, FACS, IHC (p) Host: Mouse Monoclonal 1D6 unconjugated
Catalog No. ABIN1449224
  • Target See all BAFF (TNFSF13B) Antibodies
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    Reactivity
    • 117
    • 30
    • 29
    • 2
    • 2
    • 2
    Human
    Host
    • 77
    • 37
    • 17
    • 10
    Mouse
    Clonality
    • 88
    • 53
    Monoclonal
    Conjugate
    • 73
    • 18
    • 10
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAFF antibody is un-conjugated
    Application
    • 77
    • 57
    • 48
    • 30
    • 15
    • 15
    • 13
    • 13
    • 11
    • 10
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody reacts with human BAFF/BLyS.
    Immunogen
    Human BAFF/BLyS transfectant
    Clone
    1D6
    Isotype
    IgG1
    Top Product
    Discover our top product TNFSF13B Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Protein A agarose, PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Upon receipt, store (in aliqouts) at -20 °C.
  • Target
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    Alternative Name
    CD257 / BAFF (TNFSF13B Products)
    Background
    BAFF (B cell-activating factor belonging to the TNF family) is a membrane protein expressed by dendritic cells, monocytes, macrophages, follicular dendritic cells, activated T cells, activated neutrophils, and malignant B cells. BAFF, also known as BLyS (B lymphocyte stimulator), is a potent B cell growth factor. Proteolytic cleavage can result in the release of a soluble trimeric BAFF which binds to the BAFF receptor, BCMA and TACI. The release of soluble BAFF is regulated by IFN-? and to a lesser extent IL-10. BAFF protects B cells from apoptosis and increases the expression of anti-apoptotic proteins Bcl-2 and Bcl-xL.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4
    Gene ID
    10673
    NCBI Accession
    NP_001139117
    UniProt
    Q9Y275
    Pathways
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
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