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Podoplanin antibody
PDPN
Reactivity: Mouse
WB, FACS, IP, IHC (p)
Host: Rat
Monoclonal
8F11
unconjugated
Product Details anti-Podoplanin Antibody
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Target
See all Podoplanin (PDPN) Antibodies
Podoplanin (PDPN)
Reactivity
All reactivities for Podoplanin antibodies
Mouse
Host
All hosts for Podoplanin antibodies
Rat
Clonality
All clonalities for Podoplanin antibodies
Monoclonal
Conjugate
All conjugates for Podoplanin antibodies
This Podoplanin antibody is un-conjugated
Application
All applications for Podoplanin antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody reacts with mouse Aggrus (Podoplanin). The reference 6) described that this antibody does not react to human Aggrus (Podoplanin).
Purification
Protein G agarose
Immunogen
NL-17 cell membrane fraction
Clone
8F11
Isotype
IgG2a
Top Product
Discover our top product PDPN Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
Preservative
Without preservative
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Upon receipt, store (in aliqouts) at -20 °C.
Target Details for Podoplanin
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Target
Podoplanin (PDPN)
Alternative Name
Podoplanin (PDPN Products )
Synonyms
PDPN antibody, AGGRUS antibody, GP36 antibody, GP40 antibody, Gp38 antibody, HT1A-1 antibody, OTS8 antibody, PA2.26 antibody, T1A antibody, T1A-2 antibody, OTS-8 antibody, RANDAM-2 antibody, T1-alpha antibody, T1a antibody, T1alpha antibody, E11 antibody, RTI40 antibody, podoplanin antibody, PDPN antibody, Pdpn antibody
Background
In addition to hemostasis and host defense, platelets are involved in the induction of inflammation, tissue repair, and tumor metastasis. Aggrus (T1a/Podoplanin) is a novel 36-45 kDa membrane sialoglycoprotein that induces platelet aggregation. Aggrus is highly expressed in various tumor cells and the platelet aggregation ability of Aggrus depends on specific oligosaccharide structures that may be related to the metastasis process in cancer cells. Aggrus has been identified as a diagnostic tumor marker for seminomas and testicular cancers.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha
Molecular Weight
44 kDa
Gene ID
10630
NCBI Accession
NP_001006625
UniProt
Q86YL7
Pathways
Dicarboxylic Acid Transport
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