PDIA3 antibody (C-Term)

Catalog No. ABIN1440039

Product Details anti-PDIA3 Antibody

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Monkey, Guinea Pig, Cow, Rabbit, Pig, Hamster, Horse, Goat, Sheep, Avian, Cat, Chicken, Donkey

Host: Goat

Clonality: Polyclonal

Conjugate: This PDIA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Detects a band of 60 kDa by Western blot in the following canine, human, monkey, mouse, rat whole cell lysates.

Characteristics: PDIA3 protein disulfide isomerase family A, member 3

Purification: epitope affinity purified

Immunogen: Purified recombinante peptide derived from within residues 300 aa to the C-terminus of human ERP57 produced in E. coli.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Concentration: 2 mg/mL

Buffer: Polyclonal antibody supplied as a 200 µL (2 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.

References for anti-PDIA3 antibody (ABIN1440039)

Alenquer, Vale-Costa, Etibor, Ferreira, Sousa, Amorim: "Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites." in: Nature communications, Vol. 10, Issue 1, pp. 1629, (2019) (PubMed).

Target Details for PDIA3

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Alternative Name: ERP57 (PDIA3 Products)

Background: This endoplasmic reticulum protein interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. It has disulfide isomerase activity and complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Synonyms: 58 kDa glucose regulated protein, 58 kDa microsomal protein, disulfide isomerase ER 60, endoplasmic reticulum resident protein 57, endoplasmic reticulum resident protein 60, ER protein 57, ER protein 60, ER protein 61, ERP57, ERp60, ERp61, glucose regulated protein 58 Kd, GRP57, GRP58, HsT17083, P58, PDIA3, phospholipase C alpha, PI PLC, protein disulfide isomerase A3 antibody.
Ensembl identifier: ENSG00000167004

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis