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RAB27A antibody (C-Term)

RAB27A Reactivity: Human, Mouse, Rat, Sheep, Cow, Goat, Horse, Dog, Rabbit, Guinea Pig, Monkey, Chicken, Pig, Cat, Donkey, Hamster, Avian WB, IF, IHC (p), IHC (fro) Host: Goat Polyclonal unconjugated
Catalog No. ABIN1440000
  • Target See all RAB27A Antibodies
    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
    Binding Specificity
    • 13
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 50
    • 22
    • 20
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Sheep, Cow, Goat, Horse, Dog, Rabbit, Guinea Pig, Monkey, Chicken, Pig, Cat, Donkey, Hamster, Avian
    Host
    • 42
    • 6
    • 2
    • 2
    Goat
    Clonality
    • 46
    • 6
    Polyclonal
    Conjugate
    • 30
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAB27A antibody is un-conjugated
    Application
    • 38
    • 28
    • 10
    • 8
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Detects Rab27a by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab27a. This antibody also recognizes Rab27b protein.
    Characteristics
    RAB27A, member RAS oncogene family
    Purification
    epitope affinity purified
    Immunogen
    Purified recombinant peptide derived from within residues 120 aa to the C-terminus of mouse Rab27a produced in E. coli.
    Isotype
    IgG
    Top Product
    Discover our top product RAB27A Primary Antibody
  • Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Polyclonal antibody supplied as a 200 µL (1 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide
    Handling Advice
    The antibody solution should be gently mixed before use.
    Storage
    4 °C,-20 °C
    Storage Comment
    For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.
  • Alzahofi, Welz, Robinson, Page, Briggs, Stainthorp, Reekes, Elbe, Straub, Kallemeijn, Tate, Goff, Sviderskaya, Cantero, Montoliu, Nedelec, Miles, Bailly, Kerkhoff, Hume: "Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins." in: Nature communications, Vol. 11, Issue 1, pp. 3495, (2020) (PubMed).

    Pelkonen, Reinisalo, Morin-Picardat, Kidron, Urtti: "Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160352, (2017) (PubMed).

    Reichhart, Markowski, Ishiyama, Wagner, Crespo-Garcia, Schorb, Ramalho, Milenkovic, Föckler, Seabra, Strauß: "Rab27a GTPase modulates L-type Ca2+ channel function via interaction with the II-III linker of CaV1.3 subunit." in: Cellular signalling, Vol. 27, Issue 11, pp. 2231-40, (2016) (PubMed).

  • Target
    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
    Alternative Name
    Rab27a (RAB27A Products)
    Synonyms
    MGC80943 antibody, RAB27A antibody, gs2 antibody, ram antibody, rab27 antibody, MGC89827 antibody, hst18676 antibody, zgc:114135 antibody, GS2 antibody, HsT18676 antibody, RAB27 antibody, RAM antibody, 2210402C08Rik antibody, 2410003M20Rik antibody, 4933437C11Rik antibody, ash antibody, RAB27A, member RAS oncogene family L homeolog antibody, RAB27A, member RAS oncogene family antibody, RAB27A, member RAS oncogene family S homeolog antibody, rab27a.L antibody, RAB27A antibody, rab27a antibody, rab27a.S antibody, Rab27a antibody
    Background
    Rab27a belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and involved in lysosome-related vesicle transport and small GTPase mediated signal transduction.
    Synonyms: GS2, GTP-binding protein Ram, rab-27, ras-related protein Rab-27A, RAB27, RAM.
    Ensembl identifier: ENSG00000069974
    Pathways
    Peptide Hormone Metabolism
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