RAB27A antibody (C-Term)
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- Target See all RAB27A Antibodies
- RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Sheep, Cow, Goat, Horse, Dog, Rabbit, Guinea Pig, Monkey, Chicken, Pig, Cat, Donkey, Hamster, Avian
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This RAB27A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Detects Rab27a by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab27a. This antibody also recognizes Rab27b protein.
- Characteristics
- RAB27A, member RAS oncogene family
- Purification
- epitope affinity purified
- Immunogen
- Purified recombinant peptide derived from within residues 120 aa to the C-terminus of mouse Rab27a produced in E. coli.
- Isotype
- IgG
- Top Product
- Discover our top product RAB27A Primary Antibody
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- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Polyclonal antibody supplied as a 200 µL (1 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide
- Handling Advice
- The antibody solution should be gently mixed before use.
- Storage
- 4 °C,-20 °C
- Storage Comment
- For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.
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Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins." in: Nature communications, Vol. 11, Issue 1, pp. 3495, (2020) (PubMed).
: "Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160352, (2017) (PubMed).
: "Rab27a GTPase modulates L-type Ca2+ channel function via interaction with the II-III linker of CaV1.3 subunit." in: Cellular signalling, Vol. 27, Issue 11, pp. 2231-40, (2016) (PubMed).
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Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins." in: Nature communications, Vol. 11, Issue 1, pp. 3495, (2020) (PubMed).
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- Target
- RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
- Alternative Name
- Rab27a (RAB27A Products)
- Synonyms
- MGC80943 antibody, RAB27A antibody, gs2 antibody, ram antibody, rab27 antibody, MGC89827 antibody, hst18676 antibody, zgc:114135 antibody, GS2 antibody, HsT18676 antibody, RAB27 antibody, RAM antibody, 2210402C08Rik antibody, 2410003M20Rik antibody, 4933437C11Rik antibody, ash antibody, RAB27A, member RAS oncogene family L homeolog antibody, RAB27A, member RAS oncogene family antibody, RAB27A, member RAS oncogene family S homeolog antibody, rab27a.L antibody, RAB27A antibody, rab27a antibody, rab27a.S antibody, Rab27a antibody
- Background
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Rab27a belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and involved in lysosome-related vesicle transport and small GTPase mediated signal transduction.
Synonyms: GS2, GTP-binding protein Ram, rab-27, ras-related protein Rab-27A, RAB27, RAM.
Ensembl identifier: ENSG00000069974 - Pathways
- Peptide Hormone Metabolism
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