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IFI35 antibody (PE-Cy5)

IFI35 Reactivity: Human, Mouse, Rat, Pig, Cow, Dog WB Host: Rabbit Polyclonal PE-Cy5
Catalog No. ABIN1437239
  • Target See all IFI35 Antibodies
    IFI35 (Interferon-Induced Protein 35 (IFI35))
    Reactivity
    Human, Mouse, Rat, Pig, Cow, Dog
    Host
    • 33
    • 9
    Rabbit
    Clonality
    • 36
    • 6
    Polyclonal
    Conjugate
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFI35 antibody is conjugated to PE-Cy5
    Application
    • 33
    • 17
    • 16
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IFI35
    Isotype
    IgG
    Top Product
    Discover our top product IFI35 Primary Antibody
  • Application Notes
    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IFI35 (Interferon-Induced Protein 35 (IFI35))
    Alternative Name
    IFI35 (IFI35 Products)
    Synonyms
    IFI35 antibody, IFP35 antibody, 2010008K16Rik antibody, AW986054 antibody, ifi-35 antibody, interferon induced protein 35 antibody, interferon-induced protein 35 antibody, IFI35 antibody, ifi35 antibody, Ifi35 antibody
    Background

    Synonyms: I 35, i-35, I35, P 35, P35, IN35, IN35_HUMAN, Interferon induced 35 kDa protein, Interferon-induced 35 kDa protein.

    Background: The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-? IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-?signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-? Two isoforms of IFI-35 exist due to alternative splicing events.

    Molecular Weight
    31kDa
    Gene ID
    3430
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