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EDRF1 antibody (HRP)

C10orf137 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1422244
  • Target See all EDRF1 (C10orf137) Antibodies
    EDRF1 (C10orf137) (Chromosome 10 Open Reading Frame 137 (C10orf137))
    Reactivity
    Human, Mouse, Rat
    Host
    • 15
    • 2
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EDRF1 antibody is conjugated to HRP
    Application
    • 17
    • 13
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EDRF1/C10orf137
    Isotype
    IgG
    Top Product
    Discover our top product C10orf137 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    EDRF1 (C10orf137) (Chromosome 10 Open Reading Frame 137 (C10orf137))
    Alternative Name
    EDRF1 (C10orf137 Products)
    Synonyms
    EDRF1 antibody, AU022667 antibody, AW558805 antibody, Edrf1 antibody, erythroid differentiation regulatory factor 1 antibody, chromosome 10 open reading frame 137 antibody, EDRF1 antibody, C10orf137 antibody, Edrf1 antibody
    Background

    Synonyms: C10orf137 protein, Chromosome 10 open reading frame 137, EDRF1, Erythroid dferentiation related factor 1, EDRF1_HUMAN.

    Background: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. EDRF1 (erythroid differentiation-related factor 1), also known as C10orf137 (chromosome 10 open reading frame 137), is a 1,238 amino acid protein containing two TPR repeats. Localizing to nucleus, EDRF1 is involved in transcriptional activation of globin genes by regulating DNA-binding activity of GATA-1 transcription factor. EDRF1 may also play an important role in organ development and histological differentiation. EDRF1 exists as four alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 10q26.13.

    Gene ID
    26098
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