HECA antibody (AA 260-310) (Cy5.5)
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- Target See all HECA Antibodies
- HECA (Headcase Homolog (HECA))
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Binding Specificity
- AA 260-310
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HECA antibody is conjugated to Cy5.5
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HECA
- Isotype
- IgG
- Top Product
- Discover our top product HECA Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- HECA (Headcase Homolog (HECA))
- Alternative Name
- HECA (HECA Products)
- Synonyms
- HECA antibody, si:dkey-34f16.2 antibody, HDC antibody, HDCL antibody, HHDC antibody, dJ225E12.1 antibody, Gm869 antibody, hdc homolog, cell cycle regulator antibody, Heca antibody, HECA antibody, heca antibody
- Background
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Synonyms: HDCL, Gm869, HDC, HDC_HUMAN, Headcase homolog Drosophila, Headcase protein homolog, HECA, hHDC.
Background: HECA, also known as headcase homolog, HDC, HDCL or HHDC, is a 543 amino acid mammalian homolog of the Drosophila headcase protein, a highly basic, cytplasmic peptide that plays a role in mitotic re-entry during adult morphogenesis. Expressed in a variety of tissues with highest expression in thymus, spleen and heart, HECA is thought to play a role in the development of epithelial tube networks in lung tissue and may also be involved in the pathogenesis of lung cancer. The gene encoding HECA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6 % of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
- Gene ID
- 51696
- UniProt
- Q9UBI9
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