CLLD6 antibody (HRP)

Catalog No. ABIN1421512

Product Details anti-CLLD6 Antibody (HRP)

Target: CLLD6 (C13orf1) (Chromosome 13 Open Reading Frame 1 (C13orf1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLLD6 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLLD6/C13orf1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CLLD6

Target: CLLD6 (C13orf1) (Chromosome 13 Open Reading Frame 1 (C13orf1))

Alternative Name: CLLD6 (C13orf1 Products)

Synonyms: C13orf1 antibody, CLLD6 antibody, fd05e05 antibody, MGC56247 antibody, zgc:56247 antibody, wu:fd05e05 antibody, si:dz79f24.1 antibody, dZ79F24.1-001 antibody, si:busm1-79f24.1 antibody, C1H13orf1 antibody, c13orf1 antibody, Clld6 antibody, RGD1306437 antibody, 6330409N04Rik antibody, C12H13orf1 antibody, zgc:66415 antibody, zgc:77103 antibody, SPRY domain containing 7 antibody, SPRY domain containing 7a antibody, SPRY domain containing 7 S homeolog antibody, SPRY domain containing 7b antibody, SPRYD7 antibody, spryd7a antibody, spryd7.S antibody, spryd7 antibody, Spryd7 antibody, spryd7b antibody

Background:

Synonyms: Chromosome 13 open reading frame 1, Chronic lymphocytic leukemia deletion region gene 6 protein, CLL deletion region gene 6 protein, CLLD 6, CLLD6, Hypothetical protein LOC57213, SPRY7_HUMAN.

Background: CLLD6, is a 196 amino acid protein that contains one B30.2/SPRY domain. Expression of CLLD6 is found at highest levels in heart, skeletal muscle and testis, with lower levels found in thymus, peripheral blood leukocytes, lymph node and bone marrow. Existing as two alternatively spliced isoforms, CLLD6 maps to human chromosome 13, which comprises nearly 4 % of human DNA and contains about 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival.