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FIGNL1 antibody (Cy7)

FIGNL1 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal Cy7
Catalog No. ABIN1420556
  • Target See all FIGNL1 Antibodies
    FIGNL1 (Fidgetin-Like 1 (FIGNL1))
    Reactivity
    • 40
    • 18
    • 16
    • 1
    Human, Mouse, Rat
    Host
    • 40
    Rabbit
    Clonality
    • 40
    Polyclonal
    Conjugate
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FIGNL1 antibody is conjugated to Cy7
    Application
    • 33
    • 14
    • 12
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FIGNL1
    Isotype
    IgG
    Top Product
    Discover our top product FIGNL1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    FIGNL1 (Fidgetin-Like 1 (FIGNL1))
    Alternative Name
    FIGNL1 (FIGNL1 Products)
    Synonyms
    fb82h05 antibody, wu:fb82h05 antibody, wu:fj99a11 antibody, zgc:193664 antibody, fidgetin like 1 antibody, fidgetin-like 1 antibody, fidgetin-like 1 L homeolog antibody, FIGNL1 antibody, fignl1 antibody, Fignl1 antibody, fignl1.L antibody
    Background

    Synonyms: Fidgetin like protein 1, fidgetin-like 1, FIGL1_HUMAN.

    Background: FIGNL1 is a 674 amino acid protein belonging to the AAA ATPase family. FIGNL1 exists as a hexamer that undergoes alternative splicing to produce two isoforms. FIGNL1 utilizes magnesium as a cofactor and is phosphorylated upon DNA damage, probably by ATM or ATR. FIGNL1 is suggested to regulate osteoblast proliferation and differentiation. FIGNL1 is encoded by a gene located on human chromosome 7, which consists about 158 milllion bases, encodes over 1000 genes and makes up about 5 % of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

    Gene ID
    63979
    Pathways
    Microtubule Dynamics
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