MARCH11 antibody (HRP)

Catalog No. ABIN1420060

Product Details anti-MARCH11 Antibody (HRP)

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH11 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MARCH11

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MARCH11

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Alternative Name: MARCH11 (MARCH11 Products)

Synonyms: MARCH-XI antibody, 9630025C22 antibody, RGD1559945 antibody, membrane associated ring-CH-type finger 11 antibody, membrane-associated ring finger (C3HC4) 11 antibody, MARCH11 antibody, March11 antibody

Background:

Synonyms: E3 ubiquitin-protein ligase MARCH11, MARCH-XI, March11, MARHB_HUMAN, Membrane associated ring finger C3HC4 11, Membrane-associated RING finger protein 11, Membrane-associated RING-CH protein XI.

Background: E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.

Gene ID: 441061