CECR6 antibody (Cy5)
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- Target See all CECR6 Antibodies
- CECR6 (Cat Eye Syndrome Chromosome Region, Candidate 6 (CECR6))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CECR6 antibody is conjugated to Cy5
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CECR6
- Isotype
- IgG
- Top Product
- Discover our top product CECR6 Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CECR6 (Cat Eye Syndrome Chromosome Region, Candidate 6 (CECR6))
- Alternative Name
- CECR6 (CECR6 Products)
- Synonyms
- AW048664 antibody, RGD1565302 antibody, cat eye syndrome chromosome region, candidate 6 antibody, transmembrane protein 121B antibody, CECR6 antibody, tmem121b antibody, TMEM121B antibody, Tmem121b antibody
- Background
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Synonyms: Cat eye syndrome chromosome region candidate 6, Cat eye syndrome chromosome region candidate 6 homolog human, Cat eye syndrome chromosome region candidate 6 homolog, RGD1565302, AW048664, CECR6_HUMAN.
Background: Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.
- Gene ID
- 27439
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