GPKOW antibody (AA 121-220) (Cy3)

Catalog No. ABIN1417697

Product Details anti-GPKOW Antibody (Cy3)

Target: GPKOW (G Patch Domain and KOW Motifs (GPKOW))

Binding Specificity: AA 121-220

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPKOW antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPKOW

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GPKOW

Target: GPKOW (G Patch Domain and KOW Motifs (GPKOW))

Alternative Name: GPKOW (GPKOW Products)

Synonyms: GPATC5 antibody, GPATCH5 antibody, Spp2 antibody, T54 antibody, 4432411B18 antibody, DXErtd697e antibody, DXImx41e antibody, mp:zf637-1-001655 antibody, si:dz150f13.5 antibody, t54l antibody, wu:fb38d03 antibody, zgc:152714 antibody, G patch domain and KOW motifs antibody, G-patch domain and KOW motifs antibody, Gpkow antibody, GPKOW antibody, gpkow antibody

Background:

Synonyms: G patch domain and KOW mots, G patch domain and KOW mots containing protein, G patch domain and KOW mots-containing protein, G patch domain containing 5, G patch domain containing protein 5, G patch domain-containing protein 5, GPATC5, GPATCH5, gpkow, GPKOW_HUMAN, Protein MOS2 homolog, Protein T54, SPP2, T54 antibody T54 protein.

Background: GPKOW is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.

Gene ID: 27238