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DLGAP4 antibody (AA 261-370) (Cy3)

DLGAP4 Reactivity: Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy3
Catalog No. ABIN1413285
  • Target See all DLGAP4 Antibodies
    DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))
    Binding Specificity
    • 14
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    AA 261-370
    Reactivity
    • 26
    • 15
    • 15
    Mouse, Rat
    Host
    • 38
    • 2
    Rabbit
    Clonality
    • 40
    Polyclonal
    Conjugate
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DLGAP4 antibody is conjugated to Cy3
    Application
    • 32
    • 17
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SAPAP4/DLGAP4
    Isotype
    IgG
    Top Product
    Discover our top product DLGAP4 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))
    Alternative Name
    SAPAP4/DLGAP4 (DLGAP4 Products)
    Synonyms
    DAP4 antibody, DLP4 antibody, RP5-977B1.6 antibody, SAPAP4 antibody, MGC155295 antibody, DKFZp469I1627 antibody, AI225853 antibody, BC024558 antibody, DAP-4 antibody, SAPAP-4 antibody, Sapap4 antibody, WBP16 antibody, Dap4 antibody, DLG associated protein 4 antibody, discs, large (Drosophila) homolog-associated protein 4 antibody, discs, large homolog-associated protein 4 (Drosophila) antibody, DLGAP4 antibody, dlgap4 antibody, Dlgap4 antibody
    Background

    Synonyms: DAP 4, DAP-4, DAP4, Discs, large Drosophila homolog associated protein 4, Disks large associated protein 4, Disks large-associated protein 4, DLGAP4, DLGP4_HUMAN, DLP4, PSD 95/SAP90 binding protein 4, PSD-95/SAP90-binding protein 4, RP5-977B1.6, SAP90/PSD-95-associated protein 4, SAPAP 4, SAPAP-4, SAPAP4.

    Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP4 is a 992 amino acid protein that likely localizes to the postsynaptic membrane of neurons to enhance neuronal signaling. SAPAP4 could act as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP4, DLGAP4, maps to human chromosome 20. Comprising approximately 2 % of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

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