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TTC21B antibody (AA 1221-1316) (HRP)

TTC21B Reactivity: Rat ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1412870
  • Target See all TTC21B Antibodies
    TTC21B (Tetratricopeptide Repeat Domain 21B (TTC21B))
    Binding Specificity
    AA 1221-1316
    Reactivity
    • 14
    • 1
    • 1
    Rat
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TTC21B antibody is conjugated to HRP
    Application
    • 13
    • 13
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TTC21B
    Isotype
    IgG
    Top Product
    Discover our top product TTC21B Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    TTC21B (Tetratricopeptide Repeat Domain 21B (TTC21B))
    Alternative Name
    TTC21B (TTC21B Products)
    Synonyms
    2410066K11Rik antibody, Thm1 antibody, aln antibody, mKIAA1992 antibody, RGD1565122 antibody, ATD4 antibody, IFT139 antibody, JBTS11 antibody, NPHP12 antibody, THM1 antibody, sb:cb947 antibody, tetratricopeptide repeat domain 21B antibody, Ttc21b antibody, TTC21B antibody, ttc21b antibody
    Background

    Synonyms: ATD4, JBTS11, Nbla10696, NPHP12, Putative protein product of Nbla10696, Tetratricopeptide repeat protein 21B, THM1, TPR repeat protein 21B, TT21B_HUMAN, Ttc21b.

    Background: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC21B (tetratricopeptide repeat domain 21B), also known as THM1, is a 1,316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family. Localizing to cytoplasm and cytoskeleton, TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction. TTC21B may also be involved in retrograde intraflagellar transport in cilia, and is encoded by a gene that maps to human chromosome 2q24.3.

    Gene ID
    79809
    UniProt
    Q7Z4L5
    Pathways
    Hedgehog Signaling
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