TMEM132A antibody (AA 331-430) (HRP)
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- Target See all TMEM132A Antibodies
- TMEM132A (Transmembrane Protein 132A (TMEM132A))
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Binding Specificity
- AA 331-430
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TMEM132A antibody is conjugated to HRP
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Application
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TMEM132A
- Isotype
- IgG
- Top Product
- Discover our top product TMEM132A Primary Antibody
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- Application Notes
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IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TMEM132A (Transmembrane Protein 132A (TMEM132A))
- Alternative Name
- TMEM132A (TMEM132A Products)
- Synonyms
- GBP antibody, HSPA5BP1 antibody, 6720481D13Rik antibody, Hspa5bp1 antibody, Orai1 antibody, R74613 antibody, Gbp antibody, transmembrane protein 132A antibody, TMEM132A antibody, Tmem132a antibody
- Background
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Synonyms: GBP, HSPA5-binding protein 1, HSPA5BP1, T132A_HUMAN, Tmem132a, Transmembrane protein 132A.
Background: TMEM132A is a 560 amino acid protein encoded by a gene mapping to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
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