NAV2 antibody (AA 21-120) (Cy3)

Catalog No. ABIN1411833

Product Details anti-NAV2 Antibody (Cy3)

Target: NAV2 (Neuron Navigator 2 (NAV2))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAV2 antibody is conjugated to Cy3

Application: Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NAV2/RAINB1

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NAV2

Target: NAV2 (Neuron Navigator 2 (NAV2))

Alternative Name: NAV2/RAINB1 (NAV2 Products)

Synonyms: HELAD1 antibody, POMFIL2 antibody, RAINB1 antibody, STEERIN2 antibody, UNC53H2 antibody, 5330421F07Rik antibody, AU067780 antibody, BQ960892 antibody, RAINB2 antibody, Unc53H2 antibody, mKIAA3015 antibody, Rainb1 antibody, neuron navigator 2 antibody, neuron navigator 2a antibody, NAV2 antibody, nav2 antibody, nav2a antibody, Nav2 antibody

Background:

Synonyms: HELAD1, Helicase, APC down regulated 1, KIAA1419, mCG 145366, mKIAA3015, NAV 2, Neuron navigator 2, POMFIL2, Pore membrane and/or filament interacting like protein 2, RAINB1, RAINB2, Retinoic acid inducible in neuroblastoma 1, Steerin 2, STEERIN2, Unc 53 homolog 2, Unc53H2, NAV2_HUMAN.

Background: Neuron navigator 2 (NAV2), also known as RAINB1 (retinoic acid inducible in neuroblastoma 1), POMFIL2 (pore membrane and/or filament-interacting-like protein 2), HELAD1 (helicase APC down-regulated 1), unc53H2 or steerin-2, is a 2,488 amino acid nuclear protein that plays a role in the development of sensory organs. Existing as thirteen alternatively spliced isoforms, Neuron navigator 2 displays 3' to 5' helicase activity and exonuclease activity and participates in the catalysis of ATP to ADP. Neuron navigator 2 is highly expressed in the nervous system of developing embryos and colon carcinomas, as well as in liver, brain and kidney. Lower levels of expression are found in lung, thyroid, spinal cord, heart, placenta and mammary gland. Neuron navigator 2 belongs to the Nav/unc-53 family and contains one CH (calponin-homology) domain.

Gene ID: 89797

UniProt: Q8IVL1

Pathways: Sensory Perception of Sound