RSPH4A antibody (AA 435-482) (HRP)

Catalog No. ABIN1409366

Product Details anti-RSPH4A Antibody (HRP)

Target: RSPH4A (Radial Spoke Head 4 Homolog A (RSPH4A))

Binding Specificity: AA 435-482

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSPH4A antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RSPH4A/RSHL3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RSPH4A

Target: RSPH4A (Radial Spoke Head 4 Homolog A (RSPH4A))

Alternative Name: RSPH4A/RSHL3 (RSPH4A Products)

Synonyms: CILD11 antibody, RSHL3 antibody, RSPH6B antibody, dJ412I7.1 antibody, A230081C05 antibody, Rshl3 antibody, radial spoke head 4 homolog A antibody, radial spoke head 4 homolog A (Chlamydomonas) antibody, RSPH4A antibody, Rsph4a antibody

Background:

Synonyms: CILD11, dJ412I7.1, Radial spoke head protein 4 homolog A, Radial spoke head-like protein 3, RSH4A_HUMAN, RSHL3, Rsph4a, RSPH6B, A230081C05.

Background: RSHL3 is predicted to be a component of the radial spoke head based on homology with proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. RSHL3 (radial spoke head-like protein 3), also known as radial spoke head protein 4 homolog A, is a 716 amino acid protein that belongs to the flagellar radial spoke RSP4/6 family. Mutations in the RSHL3 gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Existing as three alternatively spliced isoforms, the RSHL3 gene contains 6 exons, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly and P.falciparum, and maps to human chromosome 6q22.1.