Plexin B3 antibody (AA 354-400) (Cy3)

Catalog No. ABIN1409349

Product Details anti-Plexin B3 Antibody (Cy3)

Target: Plexin B3 (PLXNB3)

Binding Specificity: AA 354-400

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin B3 antibody is conjugated to Cy3

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Plexin B2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Plexin B3

Target: Plexin B3 (PLXNB3)

Alternative Name: Plexin B3 (PLXNB3 Products)

Synonyms: si:dkey-208p7.1 antibody, PLEXB3 antibody, PLEXR antibody, PLXN6 antibody, AI451018 antibody, Plxn6 antibody, RGD1560615 antibody, plexin B3 antibody, PLXNB3 antibody, plxnb3 antibody, Plxnb3 antibody

Background:

Synonyms: PLEXR, PLXN6, PLEXB3, Plexin-B3, PLXNB3, KIAA1206

Background: Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1.

Gene ID: 5365

UniProt: Q9ULL4