ZNF318 antibody (AA 1077-1125) (Cy3)

Catalog No. ABIN1409025

Product Details anti-ZNF318 Antibody (Cy3)

Target: ZNF318 (Znf318) (Zinc Finger Protein 318 (Znf318))

Binding Specificity: AA 1077-1125

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF318 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF318

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZNF318

Target: ZNF318 (Znf318) (Zinc Finger Protein 318 (Znf318))

Alternative Name: ZNF318 (Znf318 Products)

Synonyms: ZNF318 antibody, TZF antibody, ZFP318 antibody, 2610034E08Rik antibody, D530032D06Rik antibody, Znf318 antibody, zinc finger protein 318 antibody, ZNF318 antibody, Znf318 antibody, Zfp318 antibody

Background:

Synonyms: Endocrine Regulatory Protein, HGNC13578, HRIHFB2436, ZFP318, Zinc Finger Protein 318, ZN318_HUMAN.

Background: ZNF318 is a 2279 amino acid endocrine regulatory protein that localizes to the nucleus. Highly expressed in testis, ovaries and kidneys, ZNF318 is a co-repressor of androgen receptor (AR)-mediated transcriptional activation and is thought to regulate transcription during spermatogenesis. ZNF318 interacts with the N-terminal domain of AR and contains two matrin-type zinc fingers. Two isoforms of ZNF318, designated TZF and TZF-L, are produced due to alternative splicing events. Each of these splice variants are thought to have unique roles in transcriptional regulation. While the TZF isoform functions as a repressor of AR-mediated transcriptional activation, the TZF-L isoform is thought to enhance AR-mediated transcriptional activation.

Gene ID: 24149

Pathways: SARS-CoV-2 Protein Interactome