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Utrophin antibody (Cy3)

UTRN Reactivity: Human, Mouse, Rat FACS Host: Rabbit Polyclonal Cy3
Catalog No. ABIN1408905
  • Target See all Utrophin (UTRN) Antibodies
    Utrophin (UTRN)
    Reactivity
    Human, Mouse, Rat
    Host
    • 13
    • 3
    Rabbit
    Clonality
    • 14
    • 2
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Utrophin antibody is conjugated to Cy3
    Application
    • 10
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Utrophin
    Isotype
    IgG
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    Discover our top product UTRN Primary Antibody
  • Application Notes
    IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Utrophin (UTRN)
    Alternative Name
    Utrophin (UTRN Products)
    Synonyms
    drp antibody, dmdl antibody, drp1 antibody, DKFZp469A0710 antibody, DMDL antibody, DRP antibody, DRP1 antibody, AA589569 antibody, Dmdl antibody, utrophin L homeolog antibody, utrophin antibody, utrn.L antibody, UTRN antibody, LOAG_03796 antibody, utrn antibody, LOC100551145 antibody, Utrn antibody
    Background

    Synonyms: DMDL, DRP 1, DRP, DRP-1, DRP1, Dystrophin like protein, Dystrophin related protein 1, Dystrophin related protein, Dystrophin-related protein 1, FLJ23678, UTRN, UTRO_HUMAN, Utrophin homologous to dystrophin, Utrophin

    Background: Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.

    Gene ID
    7402
    Pathways
    Skeletal Muscle Fiber Development
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