FAT3 antibody (AA 601-800) (Cy5)
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- Target See all FAT3 Antibodies
- FAT3 (FAT Tumor Suppressor Homolog 3 (FAT3))
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Binding Specificity
- AA 601-800
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FAT3 antibody is conjugated to Cy5
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CDHF15/FAT3
- Isotype
- IgG
- Top Product
- Discover our top product FAT3 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FAT3 (FAT Tumor Suppressor Homolog 3 (FAT3))
- Alternative Name
- CDHF15/FAT3 (FAT3 Products)
- Synonyms
- CDHF15 antibody, CDHR10 antibody, 9430076A06Rik antibody, D430038H04Rik antibody, Gm1132 antibody, Gm510 antibody, MFAT3F antibody, FAT atypical cadherin 3 antibody, FAT3 antibody, Fat3 antibody
- Background
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Synonyms: Cadherin family member 15, CDHF15, CDHR10, FAT tumor suppressor homolog 3, Fat3, FAT3_HUMAN, hFat3, Protocadherin Fat 3.
Background: The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including -catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT3 (FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. Containing thirty-three cadherin domains, four EGF-like domains and one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.
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