C12orf4 antibody (Biotin)

Catalog No. ABIN1405591

Product Details anti-C12orf4 Antibody (Biotin)

Target: C12orf4 (Chromosome 12 Open Reading Frame 4 (C12orf4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C12orf4 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C12ORF4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for C12orf4

Target: C12orf4 (Chromosome 12 Open Reading Frame 4 (C12orf4))

Alternative Name: C12ORF4 (C12orf4 Products)

Synonyms: MGC53313 antibody, C12orf4 antibody, MGC79726 antibody, chromosome 12 open reading frame 4 L homeolog antibody, chromosome 1 open reading frame, human C12orf4 antibody, chromosome 12 open reading frame 4 antibody, chromosome 11 open reading frame, human C12orf4 antibody, chromosome 12 open reading frame, human C12orf4 antibody, DNA segment, Chr 6, Wayne State University 163, expressed antibody, c12orf4.L antibody, C1H12ORF4 antibody, c12orf4 antibody, C11H12orf4 antibody, C12H12orf4 antibody, C12orf4 antibody, D6Wsu163e antibody

Background:

Synonyms: chromosome 12 open reading frame 4, FLJ21158, FLJ23899, hypothetical protein LOC57102, CL004_HUMAN.

Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf4 gene product has been provisionally designated C12orf4 pending further characterization.

Gene ID: 57102