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PAPPA2 antibody (AbBy Fluor® 350)

PAPPA2 Reactivity: Human, Rat, Mouse WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN1405419
  • Target See all PAPPA2 Antibodies
    PAPPA2 (Pappalysin 2 (PAPPA2))
    Reactivity
    • 26
    • 18
    • 17
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 23
    • 3
    Rabbit
    Clonality
    • 23
    • 3
    Polyclonal
    Conjugate
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAPPA2 antibody is conjugated to AbBy Fluor® 350
    Application
    • 24
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PAPP A2
    Isotype
    IgG
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    Discover our top product PAPPA2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PAPPA2 (Pappalysin 2 (PAPPA2))
    Alternative Name
    PAPP A2 (PAPPA2 Products)
    Synonyms
    PAPP-A2 antibody, PLAC3 antibody, Pappe antibody, PAPP-E antibody, PAPPE antibody, si:dkey-39f8.1 antibody, pappalysin 2 antibody, Pappa2 antibody, PAPPA2 antibody, pappa2 antibody
    Background

    Synonyms: PAPPA 2, PAPP E, PAPP-A2, PAPP-E, PAPP2_HUMAN, PAPPA 2, PAPPA2, Pappalysin 2, Pappalysin-2, PLAC3, Pregnancy associated plasma protein A2, Pregnancy associated plasma protein E1, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1.

    Background: Pregnancy-associated plasma protein-A (Pappalysin-1 or PAPP-A), also known as Insulin-like growth factor-dependent IGF-binding protein 4 (IGFBP4) protease, is a member of the peptidase M43B family of proteins. PAPP-A, a metalloproteinase, cleaves Insulin-like growth factor binding proteins IGFBP4 and IGFBP5, releasing bound IGF. PAPP-A is primarily expressed in septa and anchoring villi in placenta and is also expressed in pregnancy serum. Levels of PAPP-A increase throughout pregnancy. Lower levels of expression can be detected in kidney, prostate, breast, ovary and endometrial tissues. PAPP-A is a secreted protein that can form homodimers, in pregnancy serum PAPP-A may also form a heterotetramer with PRG-2.

    Gene ID
    60676
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