SRI antibody (AbBy Fluor® 647)
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- Target See all SRI Antibodies
- SRI (Sorcin (SRI))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SRI antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SR1/Sorcin
- Isotype
- IgG
- Top Product
- Discover our top product SRI Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SRI (Sorcin (SRI))
- Alternative Name
- Sorcin (SRI Products)
- Synonyms
- zgc:64070 antibody, sri antibody, SRI antibody, CP-22 antibody, CP22 antibody, SCN antibody, V19 antibody, 2210417O06Rik antibody, 2900070H08Rik antibody, Sor antibody, sorcin antibody, Sorcin antibody, sorcin L homeolog antibody, sorcin S homeolog antibody, SRI antibody, sri antibody, EDI_060410 antibody, EDI_160670 antibody, EDI_002860 antibody, EDI_076560 antibody, CpipJ_CPIJ004933 antibody, CpipJ_CPIJ008581 antibody, Tsp_05707 antibody, sri.L antibody, sri.S antibody, Sri antibody
- Background
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Synonyms: 22 kDa protein, Calcium binding protein amplied in mutlidrug resistant cells, CP 22, CP-22, CP22, SCN, Sorcin class 4 gene, Sorcin, SORCN_HUMAN, SRI, V19.
Background: Sorcin is a highly conserved protein, with 95 % homology between hamster and human sorcin sequences. Sorcin has four putative Ca-binding domains, two of which exhibit strong homology to calmodulin EF hand? motifs. Calcium binding directly to sorcin has been demonstrated by in vitro assays. Sorcin is closely related to members of calpain and sarcoplasmic Ca2+-binding protein subfamilies. Sorcin undergoes calcium-dependent translocation from the cytosol to cellular membranes. Sorcin binds to and modulates ryanodine receptors and is widely distributed including heart and brain tissues. At the subcellular level, sorcin localizes to T-tubule junctions of cardiac sarcoplasmic reticulum.
- Gene ID
- 6717
- Pathways
- Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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