C2ORF44 antibody (Biotin)

Catalog No. ABIN1404823

Product Details anti-C2ORF44 Antibody (Biotin)

Target: C2ORF44 (Chromosome 2 Open Reading Frame 44 (C2ORF44))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2ORF44 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf44

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for C2ORF44

Target: C2ORF44 (Chromosome 2 Open Reading Frame 44 (C2ORF44))

Alternative Name: C2orf44 (C2ORF44 Products)

Synonyms: A430092C04 antibody, WD repeat and coiled coil containing antibody, WD repeat and coiled coil containing L homeolog antibody, WDCP antibody, wdcp.L antibody, Wdcp antibody

Background:

Synonyms: C2orf44, CB044_HUMAN, Chromosome 2 open reading frame 44, FLJ21945, PP384, WD repeat-containing protein C2orf44.

Background: The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The C2orf44 gene product has been provisionally designated C2orf44 pending further characterization.

Gene ID: 80304