AIDA antibody (Biotin)
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- Target See all AIDA Antibodies
- AIDA (Axin Interactor, Dorsalization Associated (AIDA))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AIDA antibody is conjugated to Biotin
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human C1orf180/AIDA
- Isotype
- IgG
- Top Product
- Discover our top product AIDA Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- AIDA (Axin Interactor, Dorsalization Associated (AIDA))
- Alternative Name
- C1orf80 (AIDA Products)
- Synonyms
- C1orf80 antibody, RP11-378J18.7 antibody, 2610208M17Rik antibody, BC004835 antibody, zgc:73327 antibody, AIDA antibody, axin interactor, dorsalization associated antibody, axin interactor, dorsalization associated L homeolog antibody, axin interactor, dorsalization associated S homeolog antibody, AIDA antibody, Aida antibody, aida antibody, aida.L antibody, aida.S antibody
- Background
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Synonyms: dorsalization-associated protein, AIDA, AIDA_HUMAN, Axin interaction partner and dorsalization antagonist, Axin interactor, Axin interactor, dorsalization associated, Chromosome 1 open reading frame 80, UPF0491 protein C1orf80.
Background: AIDA, also known as C1orf80, is a 306 amino acid protein that belongs to the axin interactor family. Expressed in a variety of tissues, including skeletal muscle and heart, AIDA functions as a ventralizing factor during embryogenesis, disrupting Axin homodimerization and inhibiting Axin-mediated JNK activation. Axin, a scaffold protein, is important for both JNK signaling and the canonical Wnt pathway, two processes that play an essential role in embryonic dorsoventral patterning. Disruption of Axin by AIDA results in the negative regulation of JNK and Wnt signaling, thereby affecting embryonic developmental events. Three isoforms of AIDA exist due to alternative splicing events.
- Gene ID
- 439927
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