FGF18 antibody (AA 95-145) (Biotin)

Catalog No. ABIN1404517

Product Details anti-FGF18 Antibody (Biotin)

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Binding Specificity: AA 95-145

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF18 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FGF18

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FGF18

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Alternative Name: FGF18 (FGF18 Products)

Synonyms: FGF-18 antibody, ZFGF5 antibody, D130055P09Rik antibody, fgf18 antibody, FGF18 antibody, fgf18l antibody, fibroblast growth factor 18 antibody, fibroblast growth factor 18a antibody, fibroblast growth factor 18b antibody, FGF18 antibody, Fgf18 antibody, fgf18a antibody, Tsp_09844 antibody, fgf18b antibody

Background:

Synonyms: FGF 18, FGF18, FGF-18, Fibroblast Growth Factor 18, ZFGF5, FGF18_HUMAN.

Background: FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Gene ID: 8817

UniProt: O76093

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway