ANGEL2 antibody (AbBy Fluor® 488)
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- Target See all ANGEL2 products
- ANGEL2 (Angel Homolog 2 (ANGEL2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ANGEL2 antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ANGEL2
- Isotype
- IgG
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ANGEL2 (Angel Homolog 2 (ANGEL2))
- Alternative Name
- ANGEL2 (ANGEL2 Products)
- Synonyms
- MGC115586 antibody, 2610307I21Rik antibody, 5730410O10Rik antibody, AI845692 antibody, D1Ertd396e antibody, D1Ertd654e antibody, RGD1305056 antibody, KIAA0759L antibody, angel homolog 2 antibody, angel homolog 2 S homeolog antibody, ANGEL2 antibody, angel2.S antibody, angel2 antibody, Angel2 antibody
- Background
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Synonyms: NGE2_HUMAN, Angel homolog 2, angel2, Protein angel homolog 2.
Background: ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3_5_-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.
- Gene ID
- 90806
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