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BIN2 antibody (AbBy Fluor® 350)

BIN2 Reactivity: Human, Rat, Mouse WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN1404309
  • Target See all BIN2 Antibodies
    BIN2 (Bridging Integrator 2 (BIN2))
    Reactivity
    • 47
    • 15
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 46
    • 1
    Rabbit
    Clonality
    • 46
    • 1
    Polyclonal
    Conjugate
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIN2 antibody is conjugated to AbBy Fluor® 350
    Application
    • 36
    • 18
    • 17
    • 13
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BIN2/BRAP1
    Isotype
    IgG
    Top Product
    Discover our top product BIN2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    BIN2 (Bridging Integrator 2 (BIN2))
    Alternative Name
    BIN2 (BIN2 Products)
    Synonyms
    BRAP-1 antibody, BIN2 antibody, bin2l antibody, wu:fi05e01 antibody, zgc:55758 antibody, bridging integrator 2 antibody, bridging integrator 2b antibody, BIN2 antibody, Bin2 antibody, bin2b antibody
    Background

    Synonyms: BIN2, BIN2_HUMAN, BRAP 1, Breast cancer associated protein BRAP1, Breast cancer-associated protein 1, Bridging integrator 2.

    Background: BAR proteins are characterized by a common N-terminal BAR (bin, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes. BIN1 and BIN2 are BAR proteins that share 61 % sequence similarity. BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis. BIN1 also interacts with the transcription factors c-Myc and MyoD, potentially functioning as a tumor suppressor. BIN2, also known as Breast cancer-associated protein 1, is a 565 amino acid protein that interacts with BIN1. In contrast to BIN1, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region. BIN2 shows preferred expression in tissues of hematopoietic origin, with high levels found in spleen, thymus, colon, placenta, lymphoid and granulocytic cells. There are two isoforms of BIN2 that are produced as a result of alternative splicing events.

    Gene ID
    51411
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