DENND2C antibody (AbBy Fluor® 488)
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- Target See all DENND2C products
- DENND2C (DENN/MADD Domain Containing 2C (DENND2C))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DENND2C antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DENND2C
- Isotype
- IgG
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- DENND2C (DENN/MADD Domain Containing 2C (DENND2C))
- Alternative Name
- DENND2C (DENND2C Products)
- Synonyms
- si:dkeyp-46c9.6 antibody, MGC145874 antibody, dJ1156J9.1 antibody, A930010I20Rik antibody, RGD1308197 antibody, DENN domain containing 2C antibody, DENN/MADD domain containing 2C antibody, DENND2C antibody, dennd2c antibody, Dennd2c antibody
- Background
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Synonyms: DENN/MADD domain containing 2C, dJ1156J9.1, DKFZp686G0351, DKFZp686N1631, DKFZp779P1149, FLJ37099, RP5-1156J9.1, DEN2C_HUMAN.
Background: DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8 % of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.
- Gene ID
- 163259
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