UBR7 antibody (Biotin)

Catalog No. ABIN1403671

Product Details anti-UBR7 Antibody (Biotin)

Target: UBR7 (Ubiquitin Protein Ligase E3 Component N-Recognin 7 (UBR7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBR7 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBR7/C14orf130

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for UBR7

Target: UBR7 (Ubiquitin Protein Ligase E3 Component N-Recognin 7 (UBR7))

Alternative Name: C14orf130 (UBR7 Products)

Synonyms: C14orf130 antibody, 5730410I19Rik antibody, AA589405 antibody, AW557761 antibody, RGD1359144 antibody, ubiquitin protein ligase E3 component n-recognin 7 (putative) antibody, UBR7 antibody, Ubr7 antibody

Background:

Synonyms: Chromosome 14 open reading frame 130, N recognin 7, Putative E3 ubiquitin-protein ligase UBR7, Ubiquitin protein ligase E3 component n-recognin 7 putative, UBR7, UBR 7, UBR-7, UBR7_HUMAN.

Background: Ubr7 is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.