TCF25 antibody (AbBy Fluor® 488)

Catalog No. ABIN1403596

Product Details anti-TCF25 Antibody (AbBy Fluor® 488)

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF25 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Transcription factor 25

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TCF25

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Alternative Name: Transcription factor 25 (TCF25 Products)

Synonyms: Hulp1 antibody, NULP1 antibody, PRO2620 antibody, hKIAA1049 antibody, 1100001J13Rik antibody, 1810041K11Rik antibody, D8Ertd325e antibody, Nulp1 antibody, mKIAA1049 antibody, RGD1309054 antibody, nulp1 antibody, transcription factor 25 antibody, transcription factor 25 (basic helix-loop-helix) antibody, transcription factor 25 L homeolog antibody, TCF25 antibody, Tcf25 antibody, tcf25.L antibody

Background:

Synonyms: FKSG26, hKIAA1049, NULP1, PRO2620, Hulp1, KIAA1049, Nuclear localized protein 1, Transcription factor 25 basic helix loop helix, TCF25_HUMAN.

Background: Transcription factor 25 acts as a transcriptional repressor. It has been shown to repress transcription of SRF in vitro and hence may play a role in heart development.Transcription factor 25, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Gene ID: 22980