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FECH antibody (Biotin)

FECH Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1403209
  • Target See all FECH Antibodies
    FECH (Ferrochelatase (FECH))
    Reactivity
    • 37
    • 27
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 33
    • 4
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FECH antibody is conjugated to Biotin
    Application
    • 30
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EPB41
    Isotype
    IgG
    Top Product
    Discover our top product FECH Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    FECH (Ferrochelatase (FECH))
    Alternative Name
    FECH (FECH Products)
    Synonyms
    AI894116 antibody, Fcl antibody, fch antibody, zgc:109851 antibody, EPP antibody, FCE antibody, CG2098 antibody, Dmel\\CG2098 antibody, GB15952 antibody, ferrochelatase L homeolog antibody, ferrochelatase antibody, Ferrochelatase antibody, ferrochelatase, mitochondrial antibody, ferrochelatase HemH antibody, ferrochelatase (predicted) antibody, fech.L antibody, hemH antibody, Fech antibody, FECH antibody, fech antibody, FeCH antibody, LOC409922 antibody, hem15 antibody, APH_RS01140 antibody
    Background

    Synonyms: EPP, FCE, Ferrochelatase protoporphyria, Ferrochelatase, Ferrochelatase mitochondrial, Heme synthetase, Protoheme ferro lyase, HEMH_HUMAN.

    Background: Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway, and is localised in the mitochondrion. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors). They manifest with either skin problems, or neurological complications, or occasionally both.

    Gene ID
    2235
    Pathways
    Transition Metal Ion Homeostasis
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